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Molecular Diagnostics: Fundamentals, Methods and Clinical Applications

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This exceptional resource introduces the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to professional practice in today's laboratories. With a focus on the application of molecular concepts to diagnose diseases, the 2nd Edition reflects the many advances in this rapidly developing field.
Inside, you’ll find in-depth explanations of the principles of molecular-based assays as well as reference material and trouble-shooting tips for the laboratory. Discussions of general diagnostic procedures reflect the continuing emergence of new diagnostic technologies to prepare you to meet the challenges of the future.
“I would like to say that once published the second edition of ‘Molecular Diagnostics’ would be a significant addition to the advancing science of molecular diagnostics. It would serve the multi-purpose of a textbook and a reference guide as well as troubleshooter. I can imagine it would be equally admired by the educator, student and scientist.”
Product details
Paperback: 528 pages
Publisher: F.A. Davis Company; 2 edition (December 13, 2011)
Language: English
ISBN-10: 9780803626775
ISBN-13: 978-0803626775
ASIN: 0803626770
Product Dimensions:
7.5 x 1.2 x 9.2 inches
Shipping Weight: 2.2 pounds (View shipping rates and policies)
Average Customer Review:
4.1 out of 5 stars
51 customer reviews
Amazon Best Sellers Rank:
#126,709 in Books (See Top 100 in Books)
The content is relevant and as up to date as is realistic, given the fast-changing nature of this field. I am using it as a study guide for the MB(ASCP) exam and hope it will prove useful. My concern is the gross number of typos and errors. I have written down the ones I was able to find at the 3/4 finished mark and I have over 2 pages. What about the information that I am unaware of? I expect proofreading in a textbook and this one falls far short of the mark, hence why I gave it only 3 stars.
Personally, I found this book hard to understand. To me it was not a good read and I found a few typos that made me wonder if it was even edited. It's more for a person who is at a more intermediate level rather than introductory. You can tell that the person who wrote the book clearly understands the material, but their ability to explain said material at an introductory level is elementary at best. I feel like a lot of this information got lost in translation.
This book is an author's best effort to collect disparate topics under one cover. Molecular diagnostics is a new field and there are really only two other books covering the area by co-authors Coleman and Tsongalis. Buckingham's is slightly better, as it appears to be written by one author, who co-ordinates all the content and the index. Coleman and Tsongalis serve only as editors to their books and the chapters, written by various authors, happen to represent the authors' specialties rather than contributing to a unified text. The indexes in the latter two books are sparse and do not coordinate with the content of the chapters. Nor do the figures, critical to the understanding of complicated techniques and assays, coordinate with the text of the chapters. Buckingham, however, does have a better index (not great) and her figures are text driven, rather than copied and pasted as available. A major drawback of Buckingham is the lack of proof reading, as it is full of errors and typos. Another issue is that the study questions might have written by somebody else, since some of the answers contradict or are not consistent with the material presented in the chapters. My worry as I study for the ASCP molecular biology exam is the errors which I am not aware of.
I used this book to study for my MB(ASCP) certification. It was excellent for that purpose. It covers a really wide variety of topics, has great figures and is easy to understand. It doesn't have a huge amount of depth on most topics, but it's perfect for an overview.
I got this book for school. I have background in science but very little in molecular. I found this book very tedious to read and difficult to understand. It would be good for someone in the field, but for an introductory molecular class it is too confusing. The advanced concepts boxes I skipped because I had a hard enough time getting through the chapters. Hated it. Makes the field seem more tedious than interesting.
Saved my life in my molecular pathology masters (and MB certification). All the diagrams are great, even if they’re oddly all purple and grey.
As a molecular technologist studying for the ASCP BOC exam for molecular technologist certification, this book serves as an excellent revision tool. Not only does it cover the basic concepts of molecular biology and techniques used in the lab, but also includes nice diagramatic representations, troubleshooting, advanced concepts, case studies and study questions for each section. I would highly recommend this book to anyone looking to take the ASCP certification exam or brush up on their knowledge of molecular biology in the clinical lab.
This is a must read for those laboratory professionals trying to advance their knowledge in molecular diagnostics especially for those people taking the MB(ASCP) exam. Sure it helped me pass the exam.There are just few editorial typos in this book but negligible.
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